It contains extensive statistical information concerning the demographic situation, the living conditions of Bialostokian inhabitants and the state of the economy of Białystok in 2021. In order to illustrate changes and tendencies, most data are compared with the results of the analogous surveys in 2010, 2015 and 2020 and selected information was shown in a longer retrospective. Moreover, there is a table presenting Białystok against the background of other cities which are the seats of voivod or voivodship regional councils. The data in the publication have been shown in the form of an analytical comment, tables and charts.